鎬庢牱鑳芥不鐤楅粍鏂戠棶鍙?

鐪煎簳榛勬枒鐥呭彉鍙堢ОRieger涓績鎬ц緗戣啘鐐?闈掑勾鎬у嚭琛€鎬ч粍鏂戠棶鍙?鏈棶涓哄彂鐢熶簬榛勬枒閮ㄥ強鍏跺懆鍥寸殑寮х珛鐨勬笚鍑烘€ц剦緇滆啘瑙嗙綉鑶滅棶鐏?浼存湁瑙嗙綉鑶滀笅鏂扮敓琛€綆″強鍑鴻.鏈棶鐨勬不鐤?鐩墠灝氭棤鐗規晥鐤楁硶,鍙噰鐢ㄨ緟鍔╃枟娉曪細 1. 鍙ｆ湇钁¤悇緋栭吀閿岋細姣忔50mg. 2. 鎶楁哀鍖栧墏錛氬彛鏈嶇淮鐢熺礌C鍜岀淮鐢熺礌E. 3. 嬋€鍏夋不鐤楋細鐢ㄦ縺鍏夋墍浜х敓鐨勭儹鑳?鎽ф瘉榛勬枒鍖虹殑寮傚父鏂扮敓琛€綆?嬋€鍏夊厜鍑濅粎鏄負浜嗗皝闂凡緇忓瓨鍦ㄧ殑鏂扮敓琛€綆?騫朵笉鑳介樆姝㈡柊鐨勬柊鐢熻綆＄殑褰㈡垚,鏄竴縐嶅鐥囨不鐤? 鍚屾椂,嬋€鍏夌◢涓€榪囬噺,鏈韓鍙互浣胯剦緇滆啘鏂扮敓琛€綆″鐢?涓斿闄勮繎鐨勬甯哥粍緇囦篃浜х敓鎹熷潖,瑙嗗姛鑳藉皢鍙楀埌澶х殑褰卞搷,蹇呴』璀︽儠. 4. 緇忕灣娓╃儹鐤楁硶(TTT)錛氭娉曟槸閲囩敤810nm娉㈤暱鐨勮繎綰㈠嬋€鍏?鍦ㄨ緗戣啘涓婄殑杈愬皠鐜囦負7.5W/cm2,絀塊€忓姏寮鴻€屽眻鍏夐棿璐ㄥ惛鏀跺皯,浣塊澏緇勭粐緙撴參鍗囨俯10鈩冨乏鍙?浣嗕綆浜庝紶緇熸縺鍏夊厜鍑濅駭鐢熺殑灞€閮ㄦ俯搴?闈炵壒寮傛€х殑浣滅敤浜嶤NV,瀵瑰懆鍥存甯哥粍緇囨崯浼よ緝灝?娌葷枟鍚?CNV鍐呰鏍撳艦鎴愪互鍙婂彂鐢熼儴鍒嗘垨鍏ㄩ儴CNV闂悎,騫朵績榪涘嚭琛€鍜屾笚鍑虹殑鍚告敹,鍚屾椂榪樼溮瀵逛繚鐣欎竴瀹氱殑瑙嗗姛鑳?鍥犳,TTT閫傚悎娌葷枟鍚勭CNV,鍖呮嫭闅愬尶鎬у拰鍏稿瀷鎬NV. 5. 鍏夊姩鍔涚枟娉?PDT)錛氭槸灝嗕竴縐嶇壒寮傜殑鍏夋晱鍓傛敞灝勫埌鐥呬漢鐨勮娑蹭腑,褰撹嵂鐗╁驚鐜埌瑙嗙綉鑶滄椂,鐢?89nm嬋€鍏夌収灝勬縺鍙戝厜鏁忓墏,浠庤€岀牬鍧忓紓甯哥殑鏂扮敓琛€綆?鑰屽姝ｅ父鐨勮緗戣啘緇勭粐娌℃湁鎹熶激.鎵€浠ヨ鐢ㄤ簬娌葷枟鑰佸勾鎬ч粍鏂戝彉鎬х殑CNV,鐗瑰埆鏄腑蹇冨嚬涓嬬殑CNV.璿ョ枟娉曟槸鐩墠鍥介檯涓婃柟渚?瀹夊叏鍜屾湁鏁堢殑鏂規硶. 6. 鎵嬫湳娌葷枟錛氬瑙嗙綉鑶滀笅鏂扮敓琛€綆¤啘鐨勫垏闄?榛勬枒杞綅鏈?瑙嗙綉鑶滅Щ妞嶇瓑.宸蹭負鏈棶鐨勬不鐤楀甫鏉ヤ簡甯屾湜.

瑙嗙綉鑶滅棶鍙?榛勬枒鐥呭彉)鏈変粈涔堢棁鐘? 涓績瑙嗗姏鍑忛€€,鏈変腑蹇冩殫鐐?瑙嗙墿鍙樺艦.鐜葷拑浣撴棤鐐庢€ф敼鍙?鐪煎簳鍦ㄩ粍鏂戦儴鏈夐粍鐏拌壊娓楀嚭鎬х棶鐏跺強鍑鴻,鍦嗗艦鎴栨き鍦嗗艦,杈圭晫涓嶆竻,寰殕璧?澶у皬綰︿負1/4鍀?/2瑙嗙洏鐩村緞錛圥D錛?浠?PD浠ヤ笅涓哄瑙?鐥呯伓杈圭紭澶勬湁寮у艦鎴栫幆褰㈠嚭琛€,鍋舵湁鍛堟斁灝勫艦鎺掑垪鐨勭偣鐘跺嚭琛€.鐥呯伓澶栧懆鏈変竴鑹茬礌緔婁貢甯?鐥呭彉澶у浠ヤ腑澶嚬涓轟腑蹇?鍗婂緞涓?PD鐨勮寖鍥村唴.鐥呯▼鏈湡,榛勬枒鍖哄艦鎴愰粍鐧借壊鐦㈢棔. 瑙嗙綉鑶滅棶鍙?榛勬枒鐥呭彉)闇€瑕佸仛鍝簺媯€鏌? 鑽у厜鐪煎簳琛€綆￠€犲獎媯€鏌?鍦ㄥ姩鑴夋棭鏈熸垨鍔ㄨ剦鏈?鐩稿綋浜庢笚鍑虹伓澶勬湁棰楃矑鐘?鑺辮竟鐘剁瓑澶氱褰㈡€佺殑鏂扮敓琛€綆＄綉.鍑鴻鍖洪伄钄借崸鍏?鍑鴻涓婄紭鏈夐€忛鑽у厜鍖?鍚庢湡鏂扮敓琛€綆℃湁鑽у厜緔犳笚婕忓艦鎴愬己鑽у厜鍖? 濡備綍娌葷枟 鑽墿娌葷枟鏃犳晥,嬋€鍏夊厜鍑濇槸鐩墠娌葷枟鑴夌粶鑶滄柊鐢熻綆＄殑鏈夋晥鏂規硶.鍦ㄦ椿鍔ㄦ湡,鐥呯伓浣嶄簬榛勬枒涓績1/4PD浠ュ鑰?鍙嬋€鍏夋不鐤?