杈涗紣浠栨矓

杈涗紣浠栨矓鐗囨槸璋冭剛鑽墿1..楂樿剛琛€鐥?.鍐犲績鐥?楂樿儐鍥洪唶琛€鐥囷細涓€鑸鏈嶅墏閲忎負姣忓ぉ10mg,鏅氶棿欏挎湇.鍐犲績鐥呮偅鑰呭彲浠ユ瘡澶╂櫄涓婃湇鐢?0mg浣滀負璧峰鍓傞噺,涓嶈壇鍙嶅簲涓€鑸€愬彈鎬ц壇濂?澶ч儴鍒嗕笉鑹弽搴旇交寰笖涓轟竴榪囨€?濡傛伓蹇?鑵規郴,鐨柟,娑堝寲涓嶈壇,鐦欑棐.

杈涗紣浠栨矓涓€鑸€愬彈鎬ц壇濂?澶ч儴鍒嗕笉鑹弽搴旇交寰笖涓轟竴榪囨€?鍦ㄤ複搴婂鐓ц瘯楠屼腑鍙湁灝戜簬2%鐨勭棶浜哄洜杈涗紣浠栨矓鐨勪笉鑹弽搴旇€屼腑閫斿仠鑽?鍦ㄥ凡鏈夊鐓х粍鐨勪複搴婅瘯楠屼腑,涓嶈壇鍙嶅簲(鍒嗕負鍙兘,鍙枒鎴栬偗瀹?涓庤嵂鐗╂湁鍏崇殑鍙戠敓鐜囧ぇ浜庢垨絳変簬1%鐨勬湁錛氳吂鐥?渚跨,鑳冭偁鑳€姘?鍙戠敓鐜囧湪0.5%鍀?.9%鐨勪笉鑹弽搴旀湁鐤蹭箯,鏃犲姏,澶寸棝.鍙戠幇鑲岀棶鐨勬姤鍛婂緢緗曡.涓嬪垪涓嶈壇鍙嶅簲鐨勬姤瀵兼浘鍑虹幇鍦ㄦ棤瀵圭収緇勪複搴婅瘯楠屾垨涓婂競鍚庣殑搴旂敤涓?濡傛伓蹇?鑵規郴,鐨柟,娑堝寲涓嶈壇,鐦欑棐,鑴卞彂,鏅曠湬,鑲岃倝鐥夋寷,鑲岀棝,鑳拌吅鐐?鎰熻寮傚父,澶栧懆絏炵粡鐥呭彉,鍛曞悙鍜岃傳琛€,妯汗鑲屾憾瑙ｅ拰鑲濈値/榛勭柛緗曟湁鍙戠敓.鍖呮嫭涓嬪垪涓€欏規垨澶氶」鐗瑰緛鐨勬槑鏄劇殑榪囨晱鍙嶅簲緇煎悎寰佺綍鏈夋姤瀵?濡傝綆＄緇忔€ф按鑲?鐙肩柈鏍風患鍚堝緛,椋庢箍鎬у鍙戞€ц倢鐥?鑴夌鐐?琛€灝忔澘鍑忓皯鐥?鍡滈吀鎬х矑緇嗚優澧炲,琛€娌?ESR)澧為珮,鍏寵妭鐐?鍏寵妭鐥?鑽ㄩ夯鐤?鍏夋晱鎰熸€?鍙戠儹,娼孩,鍛煎惛鍥伴毦浠ュ強涓嶉€?瀹為獙瀹ゆ鏌ュ彂鐜幫細琛€娓呮皚鍩鴻漿縐婚叾鏄捐憲鍜屾寔緇€у崌楂樼殑鎯呭喌緗曟湁鎶ュ.鑲濆姛鑳芥鏌ュ紓甯鎬負杞誨井鎴栦竴榪囨€?鏉ユ簮浜庨楠艱倢閮ㄥ垎鐨勮娓呯７閰歌倢閰告縺閰?CK)鍗囬珮鐨勬儏鍐典篃鏈夋姤鍛?

鏈搧涓虹敳鍩虹緹鎴婁簩閰拌緟閰禔(HMG-COA)榪樺師閰舵姂鍒跺墏,鎶戝埗鍐呮簮鎬ц儐鍥洪唶鐨勫悎鎴?涓鴻鑴傝皟鑺傚墏.鏂囩尞璧勬枡琛ㄦ槑,鏈夐檷浣庨珮鑴傝鐥囧鍏旇娓?鑲濊剰,涓誨姩鑴変腑鑳嗗滻閱?TC)鐨勫惈閲?闄嶄綆鏋佷綆瀵嗗害鑴傝泲鐧借儐鍥洪唶(VLDL-C),浣庡瘑搴﹁剛錏嬬櫧鑳嗗滻閱?LDL-C)姘村鉤鐨勪綔鐢?

1.鍙ｆ湇錛氬闇€瑕佸彲鎺板紑鏈嶇敤.(1)楂樿儐鍥洪唶琛€鐥囷細涓€鑸鏈嶅墏閲忎負姣忓ぉ10mg,鏅氶棿欏挎湇.瀵逛簬鑳嗗滻閱囨按騫寵交鑷充腑搴﹀崌楂樼殑鎮ｈ€?濮嬫湇鍓傞噺涓烘瘡澶?mg.鑻ラ渶璋冩暣鍓傞噺鍒欏簲闂撮殧鍥涘懆浠ヤ笂,鏈€澶у墏閲忎負姣忓ぉ40mg,鏅氶棿欏挎湇.褰撲綆瀵嗗害鑴傝泲鐧借儐鍥洪唶姘村鉤闄嶈嚦75mg/dL(1.94mmol/L)鎴栨€昏儐鍥洪唶姘村鉤闄嶈嚦140mg/dL(3.6mmol/L)浠ヤ笅鏃?搴斿噺浣庤緵浼愪粬姹€鐨勬湇鐢ㄥ墏閲?(2)綰悎瀛愬鏃忔€ч珮鑳嗗滻閱囪鐥囷細鏍規嵁瀵圭収涓村簥鐮旂┒緇撴灉,瀵圭函鍚堝瓙瀹舵棌鎬ч珮鑳嗗滻閱囪鐥囩棶浜?寤鴻杈涗紣浠栨矓40mg/d鏅氶棿欏挎湇,鎴?0mg/d鍒嗘棭鏅?0mg

杈涗紣浠栨矓涓€鑸€愬彈鎬ц壇濂?澶ч儴鍒嗕笉鑹弽搴旇交寰笖涓轟竴榪囨€?鍦ㄤ複搴婂鐓ц瘯楠屼腑鍙湁灝戜簬2%鐨勭棶浜哄洜杈涗紣浠栨矓鐨勪笉鑹弽搴旇€屼腑閫斿仠鑽?鍦ㄥ凡鏈夊鐓х粍鐨勪複搴婅瘯楠屼腑,涓嶈壇鍙嶅簲(鍒嗕負鍙兘,鍙枒鎴栬偗瀹?涓庤嵂鐗╂湁鍏崇殑鍙戠敓鐜囧ぇ浜庢垨絳変簬1%鐨勬湁錛氳吂鐥?渚跨,鑳冭偁鑳€姘?鍙戠敓鐜囧湪0.5%鍀?.9%鐨勪笉鑹弽搴旀湁鐤蹭箯,鏃犲姏,澶寸棝.鍙戠幇鑲岀棶鐨勬姤鍛婂緢緗曡.涓嬪垪涓嶈壇鍙嶅簲鐨勬姤瀵兼浘鍑虹幇鍦ㄦ棤瀵圭収緇勪複搴婅瘯楠屾垨涓婂競鍚庣殑搴旂敤涓?濡傛伓蹇?鑵規郴,鐨柟,娑堝寲涓嶈壇,鐦欑棐,鑴卞彂,鏅曠湬,鑲岃倝鐥夋寷,鑲岀棝,鑳拌吅鐐?鎰熻寮傚父,澶栧懆絏炵粡鐥呭彉,鍛曞悙鍜岃傳琛€,妯汗鑲屾憾瑙ｅ拰鑲濈値/榛勭柛緗曟湁鍙戠敓.鍖呮嫭涓嬪垪涓€欏規垨澶氶」鐗瑰緛鐨勬槑鏄劇殑榪囨晱鍙嶅簲緇煎悎寰佺綍鏈夋姤瀵?濡傝綆＄緇忔€ф按鑲?鐙肩柈鏍風患鍚堝緛,椋庢箍鎬у鍙戞€ц倢鐥?鑴夌鐐?琛€灝忔澘鍑忓皯鐥?鍡滈吀鎬х矑緇嗚優澧炲,琛€娌?ESR)澧為珮,鍏寵妭鐐?鍏寵妭鐥?鑽ㄩ夯鐤?鍏夋晱鎰熸€?鍙戠儹,娼孩,鍛煎惛鍥伴毦浠ュ強涓嶉€?瀹為獙瀹ゆ鏌ュ彂鐜幫細琛€娓呮皚鍩鴻漿縐婚叾鏄捐憲鍜屾寔緇€у崌楂樼殑鎯呭喌緗曟湁鎶ュ.鑲濆姛鑳芥鏌ュ紓甯鎬負杞誨井鎴栦竴榪囨€?鏉ユ簮浜庨楠艱倢閮ㄥ垎鐨勮娓呯７閰歌倢閰告縺閰?CK)鍗囬珮鐨勬儏鍐典篃鏈夋姤鍛?