鑳冮棿璐ㄧ槫鍖婚櫌

GISTs鍏嶇柅緇勫寲鐮旂┒琛ㄦ槑CD117錛坈-kit錛夊拰CD34涓哄叾閲嶈鏍囧織鐗?80~100錛呯殑GISTs CD117鍛堝譏婕€ц〃杈?鑰屽鉤婊戣倢緇嗚優鍜岀緇忕氦緇翠笉琛ㄨ揪CD117.60~80錛呯殑GISTs鑲跨槫緇嗚優涓?CD34鍛堝譏婕槼鎬ц〃杈?騫朵笖鑹€х殑GISTs鐨凜D34琛ㄨ揪杈冮珮.CD34琛ㄨ揪鐗瑰紓鎬у己,鍦ㄥ尯鍒獹IST s涓庡鉤婊戣倢鐦ゆ垨絏炵粡婧愭€ц偪鐦ゆ椂鍏鋒湁閲嶈浠峰€?

鑳冭偁閬撻棿璐ㄧ槫(gastrointestinal stromal tumors,GIST)鐨勬蹇墊渶鏃╃敱Mazur鍜孋lark鍦?983騫存彁鍑?浠ュ尯鍒嗕竴緇勬棦涓嶆槸騫蟲粦鑲屾潵婧愪篃涓嶆槸絏炵粡婧愭€х殑娑堝寲閬撹偪鐦?灝咷IST瀹氫箟涓哄寘鎷敓鐗╁琛屼負涓庤搗婧愪笉鏄庣殑鍏ㄩ儴鑳冭偁閬撴褰㈢粏鑳炶偪鐦?1998騫?Kindblon絳夌爺絀惰〃鏄?GIST涓庤儍鑲犻亾鑲岄棿絏炵粡涓涘懆鍥寸殑Cajal緇嗚優鐩鎬技,鍧囨湁c-kit鍩哄洜,CD117,CD34琛ㄨ揪闃蟲€?ICC涓鴻儍鑲犺搗鎼忕粏鑳?鍥犳,鏈変漢鍙堝皢鍏剁О涔嬩負鑳冭偁閬撹搗鎼忕粏鑳炶偪鐦?Gastrointestinal Pacemaker Cell Tumor,GIPACT).浣咷IST鍙彂鐢熶簬鑳冭偁閬撳,濡傚ぇ緗戣啘,鑲犵郴鑶滅瓑,涓擥IST鐦ょ粏鑳炴棤ICC鍔熻兘,鍥犳鐩墠涔熸湁璁や負GIST鍙兘涓嶆槸璧鋒簮浜嶪CC,鑰屾槸璧鋒簮浜庝笌ICC鍚屾簮鐨勫墠浣撶粏鑳烇紙闂村彾騫茬粏鑳烇級,榪欎篃鍙В閲婇儴鍒嗙槫緇嗚優涓湁鐏舵€ц倢婧愭€ф爣璁拌〃杈?